My laboratory is interested in understanding the transcriptional networks which direct the differentiation of mesenchymal stem cells into adipocytes (fat), osteoblasts (bone), and skeletal muscle.
In particular we are studying the role of CCAAT/Enhancer binding protein β (C/EBPβ), a bzip transcription factor during mesenchymal differentiation in an effort to understand loss of lean tissue (bone and muscle) and concomitant increase in adiposity that occurs in many disease states and with aging. Furthermore, we hope to explain how obesity impacts bone and muscle maintenance throughout life.
This is the place to learn about our research. To learn a bit more about life in the lab, visit the Lab Blog!
