Contact Information

Division of Physical Medicine and Rehabilitation
Dr. Shawn Marshall, Chief of Physiatry
505 Smyth Rd, Room 1104
Ottawa, Ontario
K1H 8M2
Tel.: 613-737-7350 ext. 75306

Physical Medicine and Rehabilitation Residency Program
Dr. Deanna Quon, Program Director
505 Smyth Rd, Room 1200B
Ottawa, Ontario
K1H 8M2
Tel.: 613-737-7350 ext. 75598

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Dr. Guy Trudel

Dr. Guy Trudel
Full professor

Clinical Area

Musculoskeletal Rehabilitation

Research Interests

  • Musculoskeletal effects of immobility
  • Joint contractures
  • Tendinopathies



Cégep Limoilou

Medical school




Selected Publications

  1. Guy Trudel, Elisabeth Coletta, Ian Cameron, Daniel L. Belavý, Martin Lecompte, Gabriele Armbrecht, Dieter Felsenberg, Hans Uhthoff. Resistive exercises with or without whole-body vibration prevent vertebral marrow fat accumulation during 60 days of head-down tilt bed rest in men. Journal of Applied Physiology 112:1824-1831, 2012 (Impact factor: 4.2).

  2. Guy Trudel, Stephen E. Ryan, Kawan Rakhra, Hans K. Uhthoff. Muscle Tissue Atrophy, Extramuscular and Intramuscular Fat Accumulation, and Fat Gradient after Delayed Repair of the Supraspinatus Tendon; a Comparative Study in the Rabbit. Journal of Orthopaedic Research30:781–786, 2012 (Impact factor: 3.0)

  3. Guy Trudel, Nanthan Ramachandran, Stephen E. Ryan, Kawan Rakhra, Hans K. Uhthoff. Improved Strength Of Early Versus Late Supraspinatus Tendon Repair; A Study In The Rabbit. Journal of Shoulder and Elbow Surgery 21, 828-834, 2012. (Impact factor 2.3)

  4. Clavet H, Hebert PC, Fergusson D, Doucette S, Trudel G. Joint Contractures in the Intensive Care Unit: Association with Resource Utilization and Ambulatory Status at Discharge. Disability and Rehabilitation 33:105-112, 2011. Impact factor 1.5

  5. Guy Trudel, Stephen E. Ryan, Kawan Rakhra, Hans K. Uhthoff Extra- and intramuscular fat accumulation early after rabbit supraspinatus tendon division: depiction with CT. Radiology 252:434-441, 2010. (Impact factor 6.1)

  6. Guy Trudel, Nanthan Ramachandran, Stephen E. Ryan, Kawan Rakhra, Hans K. Uhthoff. Supraspinatus Tendon Repair into a Bony Trough in the Rabbit: Mechanical Restoration and Correlative Imaging. Journal of Orthopedic Research 28:710–715, 2010 (Impact factor: 3.0)

  7. Trudel G, Michael Payne, Burkhard Mädler, Nanthan Ramachandran, Martin Lecompte, Charles Wade, Gianni Biolo, Stéphane Blanc, Richard Hughson, Lisa Bear and Hans K. Uhthoff. BoneMarrow Fat Accumulation after 60 Days of Bedrest Persisted 1 Year after Resuming Activities Along with Hemopoietic Stimulation - the WISE Study. Journal of Applied Physiology 107: 540-548, 2009. (Impact factor: 4.2)

  8. Guy Trudel, Geoffrey P Doherty, Yoichi Koike, Nanthan Ramachandran, Martin Lecompte, Laurent Dinh, Hans K Uhthoff. Restoration of strength despite low stress and abnormal imaging after Achilles injury. Medicine & Science in Sports & Exercise. 41: 2009-2016, 2009. (Impact factor: 4.1)

  9. DeVitt DL, Koike Y, Doherty GP, Ramachandran N, Dinh L, Uhthoff HK, Lecompte M and Trudel G. The ability of ultrasonography, magnetic resonance imaging and bone mineral densitometry to predict the strength of human Achilles tendons. Archives of Physical Medicine and Rehabilitation. 90:756-60, 2009. (Impact factor: 2.3)

  10. Bergouignan A, Trudel G, Simon C, Chopard A, Schoeller DA., Momken I, Votruba SB, Desage M, Burdge G, Gauquelin-Koch G, Normand S, Blanc S. Physical inactivity differentially alters dietary oleate and palmitate trafficking. Diabetes 58:367-76, 2009 (Impact factor: 8.9)

  11. Clavet H, Hebert P, Fergusson D, Doucette S and Trudel G. Joint contractures following prolonged stays in the intensive care unit. CMAJ 2008;178:653-655. (Impact factor 8.1)

  12. Trudel G, Zhou J, Uhthoff HK and Laneuville O. Four weeks of mobility after 8 weeks of immobility fails to restore normal joint motion: a preliminary study. Clin Orthop Relat Res 2008;466:1239–44. (Impact factor 2.1)

  13. Trudel G, Koike Y, Ramachandran N, Doherty G, Dinh L, Lecompte M and Uhthoff HK. Mechanical Alterations of Rabbit Achilles Tendon after Immobilization Correlate with Bone Mineral Density but not with Magnetic Resonance or Ultrasound Imaging. Archives of Physical Medicine and Rehabilitation. 2007;88:1720-6.

  14. Payne M, Uhthoff H and Trudel G. Anemia of immobility: caused by adipocyte accumulation in bone marrow. Medical Hypotheses. 2007;69:778-86.

  15. Zhou R, Koike Y, Uhthoff HK and Trudel G. Quantitative histology and ultrastructure fail to explain weakness of immobilized rabbit Achilles tendons. Archives of Physical Medicine and Rehabilitation. 2007;88:1177-84.

  16. Payne MW, Williams DR and Trudel G. Space Flight Rehabilitation. American Journal of Physical Medicine and Rehabilitation. 2007;86:583-91.

  17. Laneuville O, Zhou R, Uhthoff H and Trudel G. Genetic Influences Joint Contractures Secondary to Immobilization. Clinical Orthopaedics and Related Research 2007;456:36-41.

  18. Trudel G, Laneuville O, Uhthoff H. Joint contractures. Editorial. Clinical Orthopaedics and Related Research 2007;456:2.

  19. Trudel G, Recklies A, Laneuville O. Increased Expression of Chitinase 3-like Protein 1 Secondary to Joint Immobility. Clinical Orthopaedic and Related Research 2007; 456:92-97.

  20. Koike Y, Trudel G, Curran D, Uhthoff HK. Delayed of supraspinatus repair by up to 12 weeks does not impair enthesis formation: a quantitative histologic study in rabbits. Journal of Orthopaedic Research 2006; 24:202-10.

  21. Doherty G, Koike Y, Uhthoff HK, Lecompte M and Trudel G. Comparative anatomy of rabbit and human Achilles tendons with magnetic resonance and ultrasound imaging. Comparative Medicine2006;56:68-74.

  22. Ramachandran N, Koike Y, Poitras P, Backman D, Uhthoff HK and Trudel G. Dual cryofixation for mechanical testing of musculoskeletal tissues. IEEE Transactions in Biomedical Engineering. 2005;52:1792-5.

  23. Koike Y, Trudel G, and Uhthoff HK. Formation of a new enthesis after attachment of the supraspinatus tendon: a quantitative histologic study in rabbits. Journal of Orthopaedic Research2005;23:1433-40.

  24. Trudel G, Koike Y, Dinh L, Uhthoff HK. Thawing of frozen calcaneus bone specimens has no effect on the bone mineral density using dual energy x-ray absorptiometry: a study in rabbits and humans. Physiological Measurement 2005;26:769-777.

  25. Trudel G, Uhthoff HK, Laneuville O. Prothrombin gene expression in articular cartilage with a putative role in cartilage degeneration secondary to joint immobility. J Rheumatol 2005;32:1547-1555.

  26. Trudel G, Uhthoff HK, Laneuville O. Knee joint immobility induces Mcl-1 gene expression in articular chondrocytes. Biochemical and Biophysical Research Communications 2005;333:247-252.

  27. Trudel G, Himori K, Uhthoff HK. Contrasting alterations of apposed and unapposed articular cartilage during joint contracture formation. Arch Phys Med Rehabil 2005;86(1):90-7.

  28. Koike Y, Uhthoff HK, Doherty G, Ramachandran N, Lecompte M and Trudel G. Achilles tendonopathy. In Critical Reviews in Physical and Rehabilitation Medicine, 16(2):109-132. Grabois M, Henley EJ Editors, Begell House Inc., New York, 2004.

  29. Trudel G, Himori K, Goudreau L, Uhthoff HK. Measurement of articular cartilage surface irregularity in rat knee contracture. J Rheumatol 2003;30:2218-25.

  30. Trudel G, Jabi M, Uhthoff H. Localized and Adaptive Synoviocyte Proliferation Characteristics in Rat Knee Joint Contractures Secondary to Immobility. Arch Phys Med Rehabil 2003;84(9):1350-6.

  31. Uhthoff HK, Trudel G, Himori K. Relevance of pathology and basic research to the surgeon treating rotator cuff disease. Journal of Orthopaedic Sciences 2003;8:449-56.

  32. Uhthoff HK, Matsumoto F, Trudel G, Himori K. Early Reattachment Does Not Reverse Atrophy and Fat Accumulation of the Supraspinatus -An Experimental Study in Rabbits. Journal of Orthopaedic Research 2003;21(3):386-92.

  33. Matsumoto F, Trudel G, Uhthoff H, Backman DS. Mechanical Effects of Immobilization on the Achilles’ Tendon. Arch Phys Med Rehabil 2003; 84(5):662-7

  34. Uhthoff HK, Seki M, Backman DS, Trudel G, Himori K, Sano H. Tensile strength of the supraspinatus after reimplantation into a bony trough: an experimental study in rabbits. J Shoulder Elbow Surg 11(5):504-9, 2002.

  35. Dudek NL, Buenger UR, Trudel G. Bilateral Anterior Superior Iliac Spine Pressure Sores: A case report. Arch Phys Med Rehabil 83(10):1459-61, 2002.

  36. Kilborn S, Trudel G, Uhthoff H. Review of growth plate closure compared with age at sexual maturity and lifespan in laboratory animals. Contemp Top Lab Anim Sci
    41(5):21-6, 2002.

  37. Matsumoto F, Trudel G, Uhthoff H. High collagen type I and low collagen type III levels in knee joint contracture: an immunohistochemical study with histological correlate. Acta Orthop Scand2002;73(3):335-43.

  38. Matsumoto F, Uhthoff H, Trudel G, Loehr JF. Delayed tendon reattachment does not reverse atrophy and fat accumulation of the supraspinatus - an experimental study in rabbits. Journal of Orthopedic Research 2002;20:357-363.

  39. Trudel G, Deslauriers N, Uhthoff H, Laneuville O. Different levels of COX-1 and COX-2 enzymes in synoviocytes and chondrocytes during joint contracture formation. J Rhumatol2001;28:2066-74.

  40. Uhthoff HK, Trudel G, Matsumoto F. Growth in width of the metacarpals- An investigation in human fetuses- J Orthop Res 2001;19:352-8.

  41. Trudel G, Kilborn S, Uhthoff HK. Bone growth increases the knee flexion contracture angle- A study in the rat. Arch Phys Med Rehabil 2001;82:583-8.

  42. Trudel G, Seki M, Uhthoff HK. Optimization of perfusion decalcification for the study of bone and joint diseases. Anat Record 2000;260:222-227.

  43. Sano H, Uhthoff HK, Ishii H, Trudel G: Early reactions after reimplantation of the supraspinatus tendon into bone. J Bone Joint Surg, British Edition 2000; 82B:1072-6.

  44. Trudel G, O’Neill PA, Goudreau LA. A mechanical arthrometer to measure knee joint contracture in rats. IEEE Trans Rehabil Eng 2000;8(2):149-155.

  45. Trudel G, Seki M, Uhthoff HK. Synovial adhesions are more important than pannus proliferation in the pathogenesis of knee joint contracture following immobilization: an experimental investigation in the rat. J Rhumatol 2000;27:351-7.

  46. Trudel G, Uhthoff HK. Contractures secondary to immobility; is the restriction articular or muscular? An experimental longitudinal study in the rat knee. Arch Phys Med Rehabil 2000 Jan;81(1):6-13.

  47. Sano H, Ishii H, Trudel G, Uhthoff HK. Histologic evidence of degeneration at the insertion of three rotator cuff tendons -A comparative study using human cadaveric shoulders- JShoulder Elbow Surg 1999 Nov-Dec;8(6):574-9

  48. Trudel G, Uhthoff HK, Brown M. Extent and direction of joint motion limitation secondary to prolonged immobility. An experimental study in the rat. Arch Phys Med Rehabil 80, 1542-7, 1999.

  49. Sano H, Uhthoff HK, Backman DS, Brunet JA, Trudel G, Pham B, Ishii H. Structural disorder at the supraspinatus tendon insertion. Relation to tensile strength. JBJS (B) 80(4), 720-5, 1998.

  50. Trudel G, Jabi M, Uhthoff H. Intra-articular tissue proliferation after immobility: methods of assessment and preliminary results in rat knee joints. J Rheumatol 25, 945-50, 1998.

  51. Trudel G. Differentiating the myogenic and arthrogenic components of joint contractures. An experimental study on the rat knee joint. Int J Rehabil Res 20, 397-404, 1997.

  52. Trudel G, Kirby RL, Ackroyd-Stolarz SA, Kirkland SA. Effects of rear-wheel camber on wheelchair stability, an epidemiological and experimental study. Arch Phys Med Rehabil 78, 78-81, 1997.

  53. Odette Laneuville, H. K. Uhthoff, S. Solanki, Guy Trudel. The effects of knee immobilization on marrow adipocyte hyperplasia and hypertrophy at the proximal rat tibia epiphysis. Acta Histochemica 119.7 (2017): 759-765. (IF 1.4)

  54. Guy Trudel, Hans K. Uhthoff, Odette Laneuville. Hemolysis during and after 21 days of bedrest. Physiological Reports. 2017. (RG IF 1.6) (JCR IF summer 2018)

  55. Katherine J. Simson, Clint T. Miller, Jon Ford, Andrew Hahne, Luana Main, Timo Rantalainen, Wei-Peng Teo, Megan Teychenne, David Connell, Guy Trudel, Guoyan Zheng, Gary Thickbroom, Daniel L. Belavy. Optimising conservative management of chronic low back pain: study protocol for a randomised controlled trial. Trials. 2017 18(1), 1-13. doi:10.1186/s13063-017-1913-8. (IF 1.9)

  56. Guy Trudel, Gerd Melkus, Greg O. Cron, Hakim Louati, Adnan Sheikh, Peder E.Z. Larson, Mark Schweitzer, Peter Lapner, Hans K. Uhthoff, Odette Laneuville. Ultra-high field imaging of the rabbit supraspinatus enthesis: a 4-week time course after repair surgery and effect of channeling. J Magn Reson Imaging. 2017 Aug 2;46(2):461-467. doi: 10.1002/jmri.25589. (IF 3.1)

  57. Mehdi Kordi, Daniel L. Belavý, Gabriele Armbrecht, Adnan Sheikh, Dieter Felsenberg, Guy Trudel. Loss and re-adaptation of lumbar intervertebral disc water signal intensity after prolonged bedrest. Journal of Musculoskeletal and Neuronal Interactions 15, 294-300; 2015. (IF 1.6)

  58. Kayleigh Wong, Guy Trudel, Odette Laneuville. Noninflammatory Joint Contractures Arising From Immobility: Animal Models to Future Treatments. Review Article 848290 BioMed Research International (2015). (IF 2.1)

  59. Kayleigh Wong, Fangui Sun, Guy Trudel, Paola Sebastiani, Odette Laneuville. Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contracture” BMC Musculoskeletal Disorders 16: 125, 2015. (IF 1.7)

  60. Campbell Mark, Laneuville Odette, Guy Trudel. Knee flexion contractures in patients with osteoarthritis: clinical features and histologic characterization of the posterior capsule. PM&R 12;466-73, 2015. (IF 2.0)

  61. Guy Trudel, Hans K. Uhthoff, Odette Laneuville, Louis Goudreau. Quantitative analysis of the reversibility of knee flexion contractures with time. An experimental study using the rat model. BMC Musculoskeletal Disorders, 15: 338-44, 2014. (IF 1.7)

  62. Guy Trudel, Odette Laneuville Elizabeth Coletta, Louis Goudreau, Hans K. Uhthoff. Quantitative and Temporal Differential Recovery of Articular and Muscular Limitations of Knee Joint Contractures; Results in a Rat Model. Journal of Applied Physiology 177(7), 730-737, 2014. (IF 3.4)

  63. Campbell Mark, Trudel Guy, Wong Kayleigh, Laneuville Odette. Genome-wide gene-expression analysis of the posterior capsule in patients with osteoarthritis and knee flexion contracture Journal of Rheumatology 41: 2232-9, 2014. (IF 3.2)

  64. Hans Uhthoff, Elisabeth Coletta, Guy Trudel. The effect of timing of surgical SSP tendon repair on muscle alterations. Journal of Orthopedic Research. 32:1430-5, 2014. (IF 2.8)

  65. Heidi Clavet, Steve Doucet, Guy Trudel. Joint contractures in the intensive care unit: quality of life and function 3.3 years after hospital discharge. Disability and Rehabilitation 37, 207-213, 2014. (IF 1.9)

  66. Hans Uhthoff, Elisabeth Coletta, Guy Trudel. Intramuscular fat accumulation and muscle atrophy in the absence of muscle retraction. Bone and Joint Research, 3(4), 117-122, 2014. (IF 2.4)

Book Chapters

  1. Dudek N, Trudel G. Joint contractures. In: Essentials of PM&R, 2nd Edition. Frontera WR, Silver JK Rizzo TD, eds. Chapter 117. pp 651-5, Philadelphia, Saunders-Elsevier 2008.

  2. Uhthoff HK, Trudel G: Skelettentwicklung und Reifung des menschlichen Knies [Skeletal development and maturation of the human knee] In: Orthopädie und orthopädische Chirurgie Wirth C-J and Zichner L, eds. Band (tome): Knie, Kohn D, ed. Stuttgart, Thieme 2004:53-60.

  3. Downie JW, Trudel G. The neurogenic bladder: Disordered autonomic control. In: The autonomic Nervous System. RW Teasell, Editor. Physical Medicine and Rehabilitation: State of the Art Reviews Hanley and Belfus, Philadelphia. 10(1), 61-80, 1996.

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