Contact Information

Manon Levesque Departmental Secretary of Pathology and Laboratory Medicine
451 Smyth road,
Room 4155
Ottawa, Ontario
K1H 8M5

Telephone: 613-562-5422
Fax: 613-562-5442
Email: mlevesq2@uottawa.ca

Sheila Schnupp
Office and Residency Program Administrator (Anatomical)
Telephone: 613-562-5800 ext. 8342
Fax: 613-562-5442
Email: sschnupp@uottawa.ca

John P. Veinot, M.D., F.R.C.P.C (Canada)
Chairman, Department of Pathology and Laboratory Medicine
Tel: 613-562-5422
Fax: 613-562-5442
Email: sschnupp@uottawa.ca

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Ross W. Milne, B.Sc. (Manitoba), M.Sc. (ibid), Ph.D. (McMaster)

Ross W. Milne

Director
Laboratory of Immunochemistry, Lipoproteins and Atherosclerosis Research Group
University of Ottawa Heart Institute.

Full Professor
Department of Pathology and Laboratory Medicine
Faculty of Medicine.

Cross-appointed Professor
Department of Biochemistry, Microbiology and Immunology
Faculty of Medicine.

Member
School of Graduate Studies and Research
University of Ottawa.

Telephone: 613-761-5258
Fax: 613-761-5281
Email: rmilne@ottawaheart.ca

Areas of Interest

  • Diabetic complications
  • Atherosclerosis
  • Mitochondrial dynamics

Areas of Expertise

  • Monoclonal antibodies
  • Mouse models of diabetic complications
  • Molecular biology
  • Biochemistry

Recent Publications

  • Milne, R. and Brownstein, S. (2011) Advanced glycation end products and diabetic retinopathy. Amino Acids. In Press
  • Rabbani, N., Godfrey, L., Xue, M., Shaheen,F., Geoffrion,M., Milne, R., and Thornalley, P.J. (2011) Conversion of low density lipoprotein to the pro-atherogenic form with increased arterial proteoglycan binding and aortal retention by methylglyoxal. Diabetes In Press
  • Bancells, C., Benitezí, S., Ordóñez-Llanos,J., Öörni, K., Kovanen, P.T., Milne, R.W., and Sanchez-Quesada, J.L. (2010) Immunochemical analysis of the electronegative LDL subfraction shows that abnormal N-terminal apolipoprotein B conformation is involved in increased binding to proteoglycans. J. Biol. Chem. 286, 1125-1133
  • Felmlee, D.J., Sheridan, D.A., Bridge, S.H., Nileson, S.U., Milne, R.W., Packard, C.J., Caslake, M.J., McGlaughlin, J., Toms, G.L., Neely, D.G., AND Bassendine, M.F. (2010)  Intravascular transfer contributes to postprandial increase of very-low-density hepatitis C virus particles. Gastroenterology. 139, 1774-1783. 
  • Hodson, L., McQuaid, S.E., Humphries, S., Milne, R., Fielding, B.A., Frayn, K.N., and Karpe, F. (2010) Greater dietary fat oxidation in obese compared to lean men: an adaptive mechanism to prevent liver fat accumulation?. American Journal of Physiology Endocrinology and Metabolism 299, E584-E592.
  • Liao,W., Strube, R.W., Milne, R.W., Chen, S.Y., AND Chan, L. (2008) Cloning of apoB intrabodies: specific knockdown of apoB in HepG2 cells. Biochem. Biophys. Res. Commun. 373, 235-240.
  • Kiss, R.S., Kavalsar, N., Okuhira, K.I., Freeman, M.W., Walter, S., Milne, R.W., McPherson, R., and Marcel, Y.L. (2007) Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects. Arterioscler. Thromb. Vasc. Biol. 27, 1139-1145.
  • Heath, R.B., Karpe, F., Milne, R.W., Burdge, G.C., Wooton, S.A., and Frayn, K.N. (2007) Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state. Amer. J. Physiol. Endocr. Metab. 292 732-739.
  • Nguyen, A.T., Hirama, T., Chauhan, V., MacKenzie, R., Milne, R. (2006) Binding characteristics of a panel of monoclonal antibodies against the ligand-binding domain of the human LDL receptor. J. Lipid Res. 47, 1399-1405.
  • Braschi, S. Geoffrion, M., Nguyen, A., Gaudreau, Y. AND Milne, R.W. (2006) Apolipoprotein B (apoB) modified by glucose in vitro differs from apoB in the circulation of patients with diabetes or end-stage renal disease. Diabetologia. 49, 1394-1401.
  • Nguyen, A.T., Braschi, S., Geoffrion, M., Fong, L.G., Crooke, R.M., Graham, M.J., Young, S.G., Milne, R. (2006) A mouse monoclonal antibody specific for mouse apoB48 and apoB100 produced by immunizing “apoB39-only” mice with mouse apoB48. Biochim. Biophys. Acta. 1761, 182-185.

Chapters and Invited Reviews

  • MILNE, R. and BROWNSTEIN, S. (2009) Advanced glycation end products and diabetic retinopathy. IMARS Highlights 4, 1-14.


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Last updated: 2015.09.08