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Discussion and answer

Cellular Leiomyoma

Section from the myometrium show evidence of intramural cellular leiomyoma with degenerative changes. There is no evidence of necrosis or cytologic atypia. Mitotic activity is minimal to nil. Immunostains are obtained to confirm the histogenesis of the neoplasm. Tumor cells are positive for vimentin, SMA, desmin, CD10 and Caldesmon. The immunoprofile is more in keeping with smooth muscle origin. Endometrium is absent in the material examined.