Clinical history: 35 year old male with enlarged neck lymph nodes
Sections of this biopsy show a portion of lymph node and fat as well as skeletal muscle. There is a diffusely infiltrating lesion composed of uniform intermediate size lymphocytes with a starry sky background of tingible body macrophages. Mitotic activity is extremely high.
Using the paraffin block provided immunophenotyping shows the tumor cell population to mark with CD10, CD20, bcl-6. Labeling with Ki-67 is essentially 100%. BCL-2 is negative as is CD3, CD5, CD30, CD23, MUM-1, cyclin D1. This immunophenotype in combination with the morphologic features is characteristic of Burkitt lymphoma.
59-year-old male presents previous history of lymphoma presents with enlarged right axillary lymph node
SPECIMEN SOURCE: Right axillar lymph nodes
CLINICAL HISTORY: Lymphoma