June 2009 - Mihaela Marinescu
Clinical history: 69 year old woman with a remote history of breast and ovarian carcinoma. Presents with new liver lesions. FNAB of liver performed.
Malignant cells are present in groups and some acinar formations. The cells have high N/C ratios, coarse chromatin, prominent nucleoli and a moderate amount of moderately vacuolated cytoplasm.
Tumour cells positive for CK7 and WT1. They are negative for TTF1, CK20, and mammaglobin.
Immunoprofile is in keeping with a metastatic ovarian adenocarcinoma.
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