Dr. Zuzana Kos

Resident PGY4

Case One

Overview

Clinical history: This 34-year-old woman discovered a palpable breast mass in her left breast. Ultrasound demonstrated a suspicious hypoechoic mass at the 11 o'clock position. A core-needle biopsy was performed and showed dense fibrous tissue only. A follow-up MRI of the breast showed an area of abnormal, non-masslike enhancement, measuring 4.6 x 3.8 x 3 cm. A vacuum-assisted core needle biopsy was performed and showed benign sclerotic mammary tissue with focal lymphocytic infiltration. The patient then underwent lumpectomy, seen here. Otherwise, the patient has a history of Type 1 diabetes mellitus of almost 20-years duration.

What is the diagnosis? What other conditions can this lesion be associated with? What is the pathogenesis? Is there an increased risk of neoplasia? What is the risk of recurrence?


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