Clinical history: Solitary, 1cm nodule over forehead in a 75 year old male
What is your diagnosis?
Discussion and answer
Diagnosis - Chondrid syringoma/pleomorphic tumour of skin
Chondroid syringoma represents the cutaneous counterpart of mixed tumor of salivary glands, therefore it is also termed 'mixed tumour of the skin'. Usually occurs in middle aged and elderly patients, as a solitary, slow growing nodule (0.5 - 3cm in diameter). Common sites are head and neck region and rarely in the distal extremities.
This tumour rarely recurs even if inadequately excised. Microscopically these are well circumscribed tumours located in the dermis and subcutaneous tissue with no epidermal connection.
The tumour has an epithelial component consisting of nests, islands, ducts and tubular structures, set in a chondroid, myxoid and fibrous stroma.