Contact Information
Manon Levesque
Departmental Secretary of Pathology and Laboratory Medicine
451 Smyth road,
Room 4155
Ottawa, Ontario
CANADA K1H 8M5
Telephone: 613-562-5422
Fax: 613-562-5442
e-mail: mlevesq2@uottawa.ca

Sheila Schnupp
Office and Residency Program Administrator (Anatomical and General Pathology)
Telephone: 613-562-5800 x8342
Fax: 613-562-5442
e-mail: sschnupp@uottawa.ca

John P. Veinot, M.D., F.R.C.P.C (Canada)
Chairman, Department of Pathology and Laboratory Medicine
Tel: 613-562-5422
Fax: 613-562-5442
E-mail: sschnupp@uottawa.ca

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Francisco Diaz-Mitoma

M.D., (Mexico), Ph.D., (Alberta), FRCP(C) Medical Microbiology
Full Professor, Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine.
Cross-Appointed Professor, Department of Pathology and Laboratory Medicine, Faculty of Medicine.
Chief, Regional Virology Laboratory, Children's Hospital of Eastern Ontario

Telephone: (613) 737-7600 ext:2261
Fax: (613) 738-4825
Email: diaz@cheo.on.ca

Areas of Interest and Expertise

  • Development of vaccines for RNA viruses. Pathogenesis of herpes viruses and hepatitis C virus infections.


Recent Publications

  • Azizi A, Ghorbani M, Mojibian M, Soare, C., Naas T, Diaz-Mitoma F.  Synergistic effect of combined HIV/HCV candidate vaccine induces a higher level of CD8+ T cell-immune responses in HLA-A2.1 Mice.  Curr HIV Res. 2007 Mar; 5(2):211-9.

  • Langley PM, Predy G, Guasparini R, Law B, Diaz-Mitoma F, Whitsitt P, Tapiero B, Dionne M, Tomovici A, Mills E, Halperin SA.  An adolescent-adult formulation tetanus and diptheria toxoids adsorbed combined with acellular pertussis vaccine has comparable immunogenicity but less reactogenicity in children 4-6 years of age than a pediatric formulation acellular pertussis vaccine and diphtheria and tetanus toxoids adsorbed combined with inactivated poliomyelitis vaccine. Vaccine. 2007 Jan 22; 25(6): 1121-5.

  • Schöndorf I., Banzhoff A, Nicolay U, Diaz-Mitoma F.  Overcoming the need for a cold chain with conjugated meningococcal group C vaccine: a controlled, randomized, double-blind study in toddlers on the safety and immunogenicity of Menjugate®, stored at room temperature for 6 months Vaccine. Vaccine 2007 Jan 26; 25(7): 1175-82.

  • Tyring, SK, Diaz-Mitoma F, Padget LG, Nunez M, Poland G, Cassidy WM, Bundick ND, Li J, Chan I, Stek J, Annunziato PW and P009 study team.  Safety and Tolerability of a High Potency Zoster Vaccine in Adults >= 50 Years of Age. Vaccine. 2007 Feb 26; 25(10): 1877-83.

  • Whitley R, Diaz-Mitoma F, Hamed K.  Single-day episodic therapy for recurrent genital herpes.. Curr Med Res Opin. 2006 Jul;22(7):1307-10.

  • Azizi A, Anderson D, Ghorbani M, Gee K, Diaz-Mitoma F.  Immunogenicity of a polyvalent HIV-1 candidate vaccine based on fourteen wil gp120 proteins in golden hamsters. BMC Immunology 2006, 7:25 (31 Oct 2006). 

  • Tapiero, B, Law, B, Diaz-Mitoma F., Duval B, Langley D, Jacquet J-M. Interchangeability of Two Diptheria and Tetanus Toxids, Acellular Pertussis, Inactivated Poliovirus, Haemophilus influenzae Type b Conjugate Vaccines as a Fourth Dose in 15 to 18 Month Old Toddlers.  Vaccine. 2006; 24:4017-4023.

  • Wald A, Stacy Selke MS, Warren T, Aoki F, Sacks S, Diaz-Mitoma, F.,  Corey L. Comparative Efficacy of Famciclovir and Valacyclovir for Suppression of Recurrent Genital Herpes and Viral Shedding.  Sex Trans Dis; 2006; 33(5).

  • Fred Y. Aoki,1 Stephen Tyring, Francisco Diaz-Mitoma, Gerd Gross, Joseph Gaoand Kamal Hamed. Single-Day, Patient-Initiated Famciclovir Therapy for Recurrent Genital Herpes: A Randomized, Double-Blind, Placebo-Controlled Trial. CID 2006:42 (1 January).

  • Ghorbani M, Naas T, Azizi A, Aucoin S, Giulivi A, Anderson DE, Torres JV, Carlos MP, Diaz-Mitoma F. Comparison of Antibody and Cell-Mediated Immune Responses after Several Hepatitis C Immunization Regimens in Balb C Mice. Viral Immunology. 2005; 18 (4): 637-48..

  • Azizi A, Tadesse H, Aucoin S, Frost R, Tellier R, Naas T, Diaz-Mitoma F.  Immunogenicity to the Nucleocapsid of the SARS Coronavirus. Genetic Vaccines Ther. 2005: 3(1): 7.

  • Azizi, A, Ghorbani M, Aucoin S, Kryworuchko M, Diaz-Mitoma F.  Potency of Cell-Mediated Immune Responses to Different Combined HIV-1 Immunogens in a Humanized Murine Model. human Vaccines. 2005; 1(4): 170-176.

  • Yu-Wen Hu, Moslih I. Al-Moslih, Mahmoud Talib Al Ali, Shabnam Rahimi Khameneh, Heather Perkins, Francisco Diaz-Mitoma, Jean Nicholas Roy, Samra Uzicanin, and Earl G. Brown. Molecular Detection Method for All Known Genotypes of TT Virus (TTV) and TTV-Like Viruses in Thalassemia Patients and Healthy Individuals. J. Clin. Microbiol. 2005 43: 3747-3754. 

  • Naas Turaya, Ghorbani Masoud, Alvarez-Maya Ikuri, Lapner Michael, Kothary R, De Repentigny Y, Susantha G, Babiuk Lorne, Giulivi Antonio, Soare Catalina, Diaz-Mitoma Francisco.  Characterization of Liver Histopathology in a Transgenic Mouse Model Expressing Genotype 1A Hepatitis C Virus Core and Envelope Proteins 1 and 2. J Gen Virol. 2005; 86: 2185-2196.

  • Arbiza J, Berois M, Delfraro A, Frasbasile S, de Sierra M, Diaz-Mitoma F, Milk R, Russi J.  Genetic Characterization of Respiratory Syncytial Viruses Isolated from Consecutive Acute Respiratory Infections in a HIV Infected Child. J Clin Virol. 2005.In Press.

  • Arbiza J, Berois M, Diaz-Mitoma F, Russi J, Delfraro A, Frabasile S, de Sierra, Milk R.  Genetic characterization of respiratory Syncytial virus strains isolated from consecutive acute respiratory infections in an HIV infected child.  Swissprot ID A995V7. 2005. EMBL/GenBank/DDBJ databases.

  • Sebekova K, Feber J, Carpenter B, Shaw L, Karnauchow T, Diaz-Mitoma F, Filler G.  Tissue Viral DNA is Associated with Chronic Allograft Nephropathy.  Pediatric Transplantation.  2005; 9:598-603.

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Last updated: 2009.12.11