Contact Information

Manon Levesque Departmental Secretary of Pathology and Laboratory Medicine
451 Smyth road,
Room 4155
Ottawa, Ontario
K1H 8M5

Telephone: 613-562-5422
Fax: 613-562-5442
Email: mlevesq2@uottawa.ca

Sheila Schnupp
Office and Residency Program Administrator (Anatomical)
Telephone: 613-562-5800 ext. 8342
Fax: 613-562-5442
Email: sschnupp@uottawa.ca

John P. Veinot, M.D., F.R.C.P.C (Canada)
Chairman, Department of Pathology and Laboratory Medicine
Tel: 613-562-5422
Fax: 613-562-5442
Email: sschnupp@uottawa.ca

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Syed A. Aziz

Syed A. Aziz

B.Sc., (Biology, Karachi, Pakistan) M.Sc., (Genetics, Karachi, Pakistan) Ph.D. (Breast Cancer Genetics, Karachi, Pakistan)

Adjunct Professor, Department of Pathology and Laboratory Medicine, Faculty of Medicine.

Scientist, Toxicology Research Division, Bureau of Chemical Safety
Food Directorate, Health Products and Food Branch
Health Canada
Ottawa, Ontario
Canada
K1A 0K9

Off: 613-957-0996
Lab: 613-954-6525
Fax: 613-941-6959
Email: syed.a.aziz@hc-sc.gc.ca

Areas of Interest and Expertise

  • Immunohistochemistry (Fresh, fixed, cell suspension, single and double staining).
  • Image analysis of immunohistochemically and immunocytochemically stained cells and tissues.
  • Tumor Bio-Markers
  • In-Situ hybridization, Special stains, Tissue Microarry

Research Interests

  • Breast Cancer
  • Oncogenes
  • Angiogenesis
  • Apoptosis
  • Cancer stem cells
  • Food toxicology

Publications

  • Aziz Syed, Bondy Genevieve, Curran Ivan, Barker Michael, Kapal Kamla, Bellon Pascale -Gagnon, MacLellan Ellen,  Mehta Rekha.  Immunohistochemical analysis of Bcl-2 in Potassium Perfluorooctane Sulfonate treated Adult Sprague-Dawley Rats livers and correlated with PCNA, apoptosis and mitochondrial permeability(In preparation).
  • Aziz Syed, Bondy Genevieve, Curran Ivan, Barker Michael, Kapal Kamla, Bellon Pascale -Gagnon, MacLellan Ellen, Mehta Rekha. Analysis of, BAX and Caspases-9 in PFOS treated Adult Sprague-Dawley Rats livers by Immunohistochemistry and correlated with PCNA, apoptosis and mitochondrial membrane permeability (In preparation).
  • Aziz Syed, Bondy Genevieve, Curran Ivan, Barker Michael, Kapal Kamla, Bellon Pascale -Gagnon, MacLellan Ellen, Mehta Rekha. Cytoplasmic p53 and cytoplasmic PCNA increases apoptotic activity and Cyclin dependent kinases inhibitor p21 expression in Rats Exposed to Dietary Potassium Perfluorooctanesulfonate (PFOS): an immunohistochemical perspective (In preparation).
  • Aziz Syed, Bondy Genevieve, Curran Ivan, Barker Michael, Kapal Kamla, Bellon Pascale -Gagnon, MacLellan Ellen, Mehta Rekha. Expression of peroxisome proliferator activated receptors-α-δ/β, and – γ in Perfluorooctane Sulfonate (PFOS) treated rat livers an immunohitochemical perspective and correlation with liver fatty acid and immunomodulator effect (In preparation).
  • Jayadev Raju , Chandni Sondagar, Jennifer Robert, Syed Aziz, Don Caldwell, Elizabeth Vavasour and Rekha Mehta.  Dietary acrylamide does not increase colon aberrant crypt foci formation in male F344 rats. Accepted in Food and Chemical Toxicology.  
  • Bondy, G.S., Lefebvre, D.E., Aziz, S., Cherry, W., Coady, L., MacLellan, E., Armstrong, C., Barker, M., Cooke, G., Gaertner, D., Arnold, D.L., Mehta, R. and Rowsell, P.R. Toxicologic and immunologic effects of perinatal exposure to the brominated diphenyl ether (BDE) mixture DE-71 in the Sprague-Dawley rat. Accepted in journal Environmental Toxicology.
  • David E. Lefebvre, Ivan Curran, Syed Aziz, Rekha Mehta, and Genevieve Bondy. 2008. Immunomodulatory Effects of Dietary Potassium Perfluorooctane Sulfonate (PFOS) Exposure in Adult Sprague-Dawley Rats. Journal of Toxicology and Environmental Health, Part A,71:23,1516 — 1525,.
  • Aziz SA, Pervez S, Khan S, Kayani N & Rahbar MH. 2005. Immunohistochemical Analysis of Proliferating Cell Nuclear Antigen (PCNA) in Infiltrating Ductal Carcinoma Breast: Comparison with Clinical and Pathological Variables. JCPSP, vol. 15 (4): 225-229.
  • Aziz SA, Pervez S, Khan S, Tariq S,Kayani N, Israr M & Rahbar MH. 2003. Prognostic markers and disease outcome in pregnancy/lactation associated breast carcinoma. Pathol Res Pract. 199(1):15-21.
  • Aziz SA, Pervez S, Khan S, Kayani N & Rahbar MH. 2002. Epidermal growth factor receptor (EGFR 1) as a prognostic marker: An Immunohistochemical Study on 315 consecutive breast carcinoma patients. J Pak Med Assoc. 52(3):104-110.
  • Aziz SA, Pervez S, Khan S, Kayani N & Rahbar MH. 2001. Immunohistochemical Cathepsin-D Expression in Breast Cancer: Correlation with Established Pathological Parameters and Survival. Pathol Res Pract. 197(8):551-557.
  • Aziz SA, Pervez S, Khan S, Kayani N, Azam SI & Rahbar MH. 2001. Prognostic markers and disease outcome in inflammatory breast carcinoma. A unique clinical experience. Breast J. 7(6):398-404.
  • Aziz SA, Pervez S, Khan S, Kayani N, Azam SI & Rahbar MH. 2001. Significance of immunohistochemical C-erbB-2 product localisation pattern for prognosis in human breast cancer. Pathol Oncol Res. 7(3):190-196.
  • Aziz SA, Pervez S, Khan S, Kayani N & Rahbar MH. 2001. Relationship of p53 expression with nodal metastases and disease out come. A prospective study on 315 consecutive breast carcinoma patients. Malays J Pathol. 23(2):65-71.

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